Conditional deletion of β1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality

Conditional deletion of β1 integrins in the intestinal epithelium, unlike in epidermal and mammary epithelia, of mice does not result in decreased cell adhesion and proliferation, but instead causes a profound increase in epithelial proliferation with dysplasia and polypoid structures. The increased...

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Detalles Bibliográficos
Autores principales: Jones, Robert G., Li, Xiufen, Gray, Phillip D., Kuang, Jinqiu, Clayton, Frederic, Samowitz, Wade S., Madison, Blair B., Gumucio, Deborah L., Kuwada, Scott K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064526/
https://www.ncbi.nlm.nih.gov/pubmed/17088430
http://dx.doi.org/10.1083/jcb.200602160

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