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Neurofascin assembles a specialized extracellular matrix at the axon initial segment
Action potential initiation and propagation requires clustered Na(+) (voltage-gated Na(+) [Nav]) channels at axon initial segments (AIS) and nodes of Ranvier. In addition to ion channels, these domains are characterized by cell adhesion molecules (CAMs; neurofascin-186 [NF-186] and neuron glia–relat...
Autores principales: | Hedstrom, Kristian L., Xu, Xiaorong, Ogawa, Yasuhiro, Frischknecht, Renato, Seidenbecher, Constanze I., Shrager, Peter, Rasband, Matthew N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064550/ https://www.ncbi.nlm.nih.gov/pubmed/17709431 http://dx.doi.org/10.1083/jcb.200705119 |
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