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SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER
Protein quality control in the endoplasmic reticulum (ER) involves recognition of misfolded proteins and dislocation from the ER lumen into the cytosol, followed by proteasomal degradation. Viruses have co-opted this pathway to destroy proteins that are crucial for host defense. Examination of dislo...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064567/ https://www.ncbi.nlm.nih.gov/pubmed/17043138 http://dx.doi.org/10.1083/jcb.200605196 |