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High levels of Notch signaling down-regulate Numb and Numblike
Inhibition of Notch signaling by Numb is critical for many cell fate decisions. In this study, we demonstrate a more complex relationship between Notch and the two vertebrate Numb homologues Numb and Numblike. Although Numb and Numblike at low levels of Notch signaling negatively regulated Notch, hi...
Autores principales: | Chapman, Gavin, Liu, Lining, Sahlgren, Cecilia, Dahlqvist, Camilla, Lendahl, Urban |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064589/ https://www.ncbi.nlm.nih.gov/pubmed/17116748 http://dx.doi.org/10.1083/jcb.200602009 |
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