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Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid

Alzheimer's Disease (AD) is defined histopathologically by extracellular β-amyloid (Aβ) fibrils plus intraneuronal tau filaments. Studies of transgenic mice and cultured cells indicate that AD is caused by a pathological cascade in which Aβ lies upstream of tau, but the steps that connect Aβ to...

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Detalles Bibliográficos
Autores principales:	King, Michelle E., Kan, Ho-Man, Baas, Peter W., Erisir, Alev, Glabe, Charles G., Bloom, George S.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064590/ https://www.ncbi.nlm.nih.gov/pubmed/17101697 http://dx.doi.org/10.1083/jcb.200605187

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