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A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane
The type II inner nuclear membrane protein emerin is a component of the LINC complex that connects the nuclear lamina to the actin cytoskeleton. In emerin-null or -deficient human dermal fibroblasts we find that the centrosome is detached from the nucleus. Moreover, following siRNA knockdown of emer...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064615/ https://www.ncbi.nlm.nih.gov/pubmed/17785515 http://dx.doi.org/10.1083/jcb.200702026 |