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Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility
We have analyzed the spontaneous symmetry breaking and initiation of actin-based motility in keratocytes (fish epithelial cells). In stationary keratocytes, the actin network flow was inwards and radially symmetric. Immediately before motility initiation, the actin network flow increased at the pros...
Autores principales: | Yam, Patricia T., Wilson, Cyrus A., Ji, Lin, Hebert, Benedict, Barnhart, Erin L., Dye, Natalie A., Wiseman, Paul W., Danuser, Gaudenz, Theriot, Julie A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064654/ https://www.ncbi.nlm.nih.gov/pubmed/17893245 http://dx.doi.org/10.1083/jcb.200706012 |
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