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The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways

Bacterial toxins and effector proteins hijack eukaryotic enzymes that are spatially localized and display rapid signaling kinetics. However, the molecular mechanisms by which virulence factors engage highly dynamic substrates in the host cell environment are poorly understood. Here, we demonstrate t...

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Detalles Bibliográficos
Autores principales: Alto, Neal M., Weflen, Andrew W., Rardin, Matthew J., Yarar, Defne, Lazar, Cheri S., Tonikian, Raffi, Koller, Antonius, Taylor, Susan S., Boone, Charles, Sidhu, Sachdev S., Schmid, Sandra L., Hecht, Gail A., Dixon, Jack E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064658/
https://www.ncbi.nlm.nih.gov/pubmed/17893247
http://dx.doi.org/10.1083/jcb.200705021