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Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination

Differential modifications of proliferating cell nuclear antigen (PCNA) determine DNA repair pathways at stalled replication forks. In yeast, PCNA monoubiquitination by the ubiquitin ligase (E3) yRad18 promotes translesion synthesis (TLS), whereas the lysine-63–linked polyubiquitination of PCNA by y...

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Detalles Bibliográficos
Autores principales:	Motegi, Akira, Sood, Raman, Moinova, Helen, Markowitz, Sanford D., Liu, Pu Paul, Myung, Kyungjae
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064669/ https://www.ncbi.nlm.nih.gov/pubmed/17130289 http://dx.doi.org/10.1083/jcb.200606145

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