Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

Cancer cells exhibit increased glycolysis for ATP production due, in part, to respiration injury (the Warburg effect). Because ATP generation through glycolysis is less efficient than through mitochondrial respiration, how cancer cells with this metabolic disadvantage can survive the competition wit...

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Detalles Bibliográficos
Autores principales: Pelicano, Hélène, Xu, Rui-hua, Du, Min, Feng, Li, Sasaki, Ryohei, Carew, Jennifer S., Hu, Yumin, Ramdas, Latha, Hu, Limei, Keating, Michael J., Zhang, Wei, Plunkett, William, Huang, Peng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064701/
https://www.ncbi.nlm.nih.gov/pubmed/17158952
http://dx.doi.org/10.1083/jcb.200512100

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