Actin turnover–dependent fast dissociation of capping protein in the dendritic nucleation actin network: evidence of frequent filament severing

Actin forms the dendritic nucleation network and undergoes rapid polymerization-depolymerization cycles in lamellipodia. To elucidate the mechanism of actin disassembly, we characterized molecular kinetics of the major filament end-binding proteins Arp2/3 complex and capping protein (CP) using singl...

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Detalles Bibliográficos
Autores principales: Miyoshi, Takushi, Tsuji, Takahiro, Higashida, Chiharu, Hertzog, Maud, Fujita, Akiko, Narumiya, Shuh, Scita, Giorgio, Watanabe, Naoki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064704/
https://www.ncbi.nlm.nih.gov/pubmed/17178911
http://dx.doi.org/10.1083/jcb.200604176

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