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Chromosome orientation
Precise chromosome segregation during cell division results from the attachment of chromosomes to microtubules emanating from both poles of the spindle apparatus. The molecular machinery involved in establishing and maintaining properly oriented microtubule attachments remains murky. Some clarity is...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064753/ https://www.ncbi.nlm.nih.gov/pubmed/17954603 http://dx.doi.org/10.1083/jcb.200709152 |
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author | Compton, Duane A. |
author_facet | Compton, Duane A. |
author_sort | Compton, Duane A. |
collection | PubMed |
description | Precise chromosome segregation during cell division results from the attachment of chromosomes to microtubules emanating from both poles of the spindle apparatus. The molecular machinery involved in establishing and maintaining properly oriented microtubule attachments remains murky. Some clarity is now emerging with the identification of Bod1 (Biorientation Defective 1), a protein that promotes chromosome biorientation by unleashing chromosomes from improperly oriented microtubule attachments. |
format | Text |
id | pubmed-2064753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-20647532008-04-22 Chromosome orientation Compton, Duane A. J Cell Biol Reviews Precise chromosome segregation during cell division results from the attachment of chromosomes to microtubules emanating from both poles of the spindle apparatus. The molecular machinery involved in establishing and maintaining properly oriented microtubule attachments remains murky. Some clarity is now emerging with the identification of Bod1 (Biorientation Defective 1), a protein that promotes chromosome biorientation by unleashing chromosomes from improperly oriented microtubule attachments. The Rockefeller University Press 2007-10-22 /pmc/articles/PMC2064753/ /pubmed/17954603 http://dx.doi.org/10.1083/jcb.200709152 Text en Copyright © 2007, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Reviews Compton, Duane A. Chromosome orientation |
title | Chromosome orientation |
title_full | Chromosome orientation |
title_fullStr | Chromosome orientation |
title_full_unstemmed | Chromosome orientation |
title_short | Chromosome orientation |
title_sort | chromosome orientation |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064753/ https://www.ncbi.nlm.nih.gov/pubmed/17954603 http://dx.doi.org/10.1083/jcb.200709152 |
work_keys_str_mv | AT comptonduanea chromosomeorientation |