Cargando…
DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?
The DNA-dependent protein kinase (DNA-PK) is one of the central enzymes involved in DNA double-strand break (DSB) repair. It facilitates proper alignment of the two ends of the broken DNA molecule and coordinates access of other factors to the repair complex. We discuss the latest findings on DNA-PK...
Autores principales: | Weterings, Eric, Chen, David J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064754/ https://www.ncbi.nlm.nih.gov/pubmed/17938249 http://dx.doi.org/10.1083/jcb.200705106 |
Ejemplares similares
-
Nonhomologous DNA End Joining in Cell-Free Extracts
por: Sharma, Sheetal, et al.
Publicado: (2010) -
Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining
por: Tsai, Chun J., et al.
Publicado: (2013) -
Coincident In Vitro Analysis of DNA-PK-Dependent and -Independent Nonhomologous End Joining
por: Hendrickson, Cynthia L., et al.
Publicado: (2010) -
Evidence for an inositol hexakisphosphate-dependent role for Ku in mammalian nonhomologous end joining that is independent of its role in the DNA-dependent protein kinase
por: Cheung, Joyce C.Y., et al.
Publicado: (2008) -
Reconstitution of Mycobacterium marinum Nonhomologous DNA End Joining Pathway in Leishmania
por: Zhang, Wen-Wei, et al.
Publicado: (2022)