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Positive feedback between Cdc42 activity and H(+) efflux by the Na-H exchanger NHE1 for polarity of migrating cells

A fundamental feature of cell polarity in response to spatial cues is asymmetric amplification of molecules generated by positive feedback signaling. We report a positive feedback loop between the guanosine triphosphatase Cdc42, a central determinant in eukaryotic cell polarity, and H(+) efflux by N...

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Detalles Bibliográficos
Autores principales:	Frantz, Christian, Karydis, Anastasios, Nalbant, Perihan, Hahn, Klaus M., Barber, Diane L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064788/ https://www.ncbi.nlm.nih.gov/pubmed/17984318 http://dx.doi.org/10.1083/jcb.200704169

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