Cargando…
The beginning of kinesin's force-generating cycle visualized at 9-Å resolution
We have used cryo-electron microscopy of kinesin-decorated microtubules to resolve the structure of the motor protein kinesin's crucial nucleotide response elements, switch I and the switch II helix, in kinesin's poorly understood nucleotide-free state. Both of the switch elements undergo...
Autores principales: | Sindelar, Charles V., Downing, Kenneth H. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064809/ https://www.ncbi.nlm.nih.gov/pubmed/17470637 http://dx.doi.org/10.1083/jcb.200612090 |
Ejemplares similares
-
High-resolution structures of kinesin on microtubules provide a basis for
nucleotide-gated force-generation
por: Shang, Zhiguo, et al.
Publicado: (2014) -
A seesaw model for intermolecular gating in the kinesin motor protein
por: Sindelar, Charles V.
Publicado: (2011) -
The yeast kinesin-5 Cin8 interacts with the microtubule in a noncanonical manner
por: Bell, Kayla M., et al.
Publicado: (2017) -
Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules
por: Liu, Daifei, et al.
Publicado: (2017) -
On the use of thermal forces to probe kinesin’s response to force
por: Chang, Chuan, et al.
Publicado: (2023)