Cargando…

Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

Integrin-linked kinase (ILK) links integrins to the actin cytoskeleton and is believed to phosphorylate several target proteins. We report that a keratinocyte-restricted deletion of the ILK gene leads to epidermal defects and hair loss. ILK-deficient epidermal keratinocytes exhibited a pronounced in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lorenz, Katrin, Grashoff, Carsten, Torka, Robert, Sakai, Takao, Langbein, Lutz, Bloch, Wilhelm, Aumailley, Monique, Fässler, Reinhard
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064816/ https://www.ncbi.nlm.nih.gov/pubmed/17485490 http://dx.doi.org/10.1083/jcb.200608125

Ejemplares similares

α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity
por: Altstätter, Johannes, et al.
Publicado: (2020)

Signaling Involved in Hair Follicle Morphogenesis and Development
por: Rishikaysh, Pisal, et al.
Publicado: (2014)

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells
por: Morgner, Jessica, et al.
Publicado: (2015)

Hierarchical patterning modes orchestrate hair follicle morphogenesis
por: Glover, James D., et al.
Publicado: (2017)

Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
por: Lin, Xiangyu, et al.
Publicado: (2022)

Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
por: Park, Sangbum
Publicado: (2022)

Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion
por: Fischer, Lisa S., et al.
Publicado: (2021)

Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle
por: Jing, Jing, et al.
Publicado: (2021)

Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation
por: Mill, Pleasantine, et al.
Publicado: (2009)

Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain
por: Sakai, Takao, et al.
Publicado: (1998)

Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
por: Molè, Matteo Amitaba, et al.
Publicado: (2021)

Planar Polarization in Embryonic Epidermis Orchestrates Global Asymmetric Morphogenesis of Hair Follicles
por: Devenport, Danelle, et al.
Publicado: (2008)

Enpp2/Autotaxin in Dermal Papilla Precursors is Dispensable for Hair Follicle Morphogenesis
por: Grisanti, Laura, et al.
Publicado: (2013)

miR-24 affects hair follicle morphogenesis targeting Tcf-3
por: Amelio, I, et al.
Publicado: (2013)

Atlas of Prenatal Hair Follicle Morphogenesis Using the Pig as a Model System
por: Jiang, Yao, et al.
Publicado: (2021)

A Single-cell Transcriptome Atlas of Cashmere Goat Hair Follicle Morphogenesis
por: Ge, Wei, et al.
Publicado: (2021)

Conditional Ablation of β1 Integrin in Skin: Severe Defects in Epidermal Proliferation, Basement Membrane Formation, and Hair Follicle Invagination
por: Raghavan, Srikala, et al.
Publicado: (2000)

A Signaling Pathway Involving TGF-β2 and Snail in Hair Follicle Morphogenesis
por: Jamora, Colin, et al.
Publicado: (2005)

β1 Integrin-Mediated Adhesion Signalling Is Essential for Epidermal Progenitor Cell Expansion
por: Piwko-Czuchra, Aleksandra, et al.
Publicado: (2009)

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis
por: Polkoff, Kathryn M., et al.
Publicado: (2022)

Gorab is required for dermal condensate cells to respond to hedgehog signals during hair follicle morphogenesis
por: Liu, Ying, et al.
Publicado: (2015)

Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis
por: Peled, Alon, et al.
Publicado: (2016)

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat
por: Wang, Shanhe, et al.
Publicado: (2020)

Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
por: Abe, Yoshinori, et al.
Publicado: (2017)

Hair follicle epidermal stem cells define a niche for tactile sensation
por: Cheng, Chun-Chun, et al.
Publicado: (2018)

Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
por: Abreu, Carla M., et al.
Publicado: (2021)

Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
por: Petridis, Christos, et al.
Publicado: (2018)

Integrin-mediated mechanotransduction
por: Sun, Zhiqi, et al.
Publicado: (2016)

β1 Integrin Is Essential for Teratoma Growth and Angiogenesis
por: Bloch, Wilhelm, et al.
Publicado: (1997)

Correction: Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment
por: Abreu, Carla M., et al.
Publicado: (2023)

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation
por: DeRouen, Mindy C, et al.
Publicado: (2010)

Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats
por: Gao, Ye, et al.
Publicado: (2016)

Chi-miR-370-3p regulates hair follicle morphogenesis of Inner Mongolian cashmere goats
por: Hai, Erhan, et al.
Publicado: (2021)

An important role of podoplanin in hair follicle growth
por: Yoon, Sun-Young, et al.
Publicado: (2019)

Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
por: Baker, Christopher M., et al.
Publicado: (2010)

Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity
por: Joost, Simon, et al.
Publicado: (2016)

Microbiome in the hair follicle of androgenetic alopecia patients
por: Ho, Bryan Siu-Yin, et al.
Publicado: (2019)

EGFR-Ras-Raf Signaling in Epidermal Stem Cells: Roles in Hair Follicle Development, Regeneration, Tissue Remodeling and Epidermal Cancers
por: Doma, Eszter, et al.
Publicado: (2013)

Hair Graying Regulators Beyond Hair Follicle
por: Chen, Jing, et al.
Publicado: (2022)

Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders
por: Gu, Yueting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i05427gcn8k3ne3g9l4c01oum3