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Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C
Ubiquitin-mediated proteolysis is critical for the alternation between DNA replication and mitosis and for the key regulatory events in mitosis. The anaphase-promoting complex/cyclosome (APC/C) is a conserved ubiquitin ligase that has a fundamental role in regulating mitosis and the cell cycle in al...
Autores principales: | Di Fiore, Barbara, Pines, Jonathon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064829/ https://www.ncbi.nlm.nih.gov/pubmed/17485488 http://dx.doi.org/10.1083/jcb.200611166 |
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