DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction

DNA methylation has been implicated in chromatin condensation and nuclear organization, especially at sites of constitutive heterochromatin. How this is mediated has not been clear. In this study, using mutant mouse embryonic stem cells completely lacking in DNA methylation, we show that DNA methyla...

Descripción completa

Detalles Bibliográficos
Autores principales: Gilbert, Nick, Thomson, Inga, Boyle, Shelagh, Allan, James, Ramsahoye, Bernard, Bickmore, Wendy A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064831/
https://www.ncbi.nlm.nih.gov/pubmed/17485486
http://dx.doi.org/10.1083/jcb.200607133

Ejemplares similares

Ejemplares similares