Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo

The Notch ligands Dll1 and Dll3 are coexpressed in the presomitic mesoderm of mouse embryos. Despite their coexpression, mutations in Dll1 and Dll3 cause strikingly different defects. To determine if there is any functional equivalence, we replaced Dll1 with Dll3 in mice. Dll3 does not compensate fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Geffers, Insa, Serth, Katrin, Chapman, Gavin, Jaekel, Robert, Schuster-Gossler, Karin, Cordes, Ralf, Sparrow, Duncan B., Kremmer, Elisabeth, Dunwoodie, Sally L., Klein, Thomas, Gossler, Achim
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064846/
https://www.ncbi.nlm.nih.gov/pubmed/17664336
http://dx.doi.org/10.1083/jcb.200702009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064846/
https://www.ncbi.nlm.nih.gov/pubmed/17664336
http://dx.doi.org/10.1083/jcb.200702009

Ejemplares similares