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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity

Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease separase. Separase also promotes centriole diseng...

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Detalles Bibliográficos
Autores principales:	Thein, Kerstin H., Kleylein-Sohn, Julia, Nigg, Erich A., Gruneberg, Ulrike
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064855/ https://www.ncbi.nlm.nih.gov/pubmed/17664331 http://dx.doi.org/10.1083/jcb.200701163

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