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Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
BACKGROUND: The mechanisms involved in the induction and regulation of inflammation resulting in dopaminergic (DA) neurotoxicity in Parkinson's disease (PD) are complex and incompletely understood. Microglia-mediated inflammation has recently been implicated as a critical mechanism responsible...
Autores principales: | Qian, Li, Xu, Zongli, Zhang, Wei, Wilson, Belinda, Hong, Jau-Shyong, Flood, Patrick M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central|1
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064906/ https://www.ncbi.nlm.nih.gov/pubmed/17880684 http://dx.doi.org/10.1186/1742-2094-4-23 |
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