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Evolutionarily Conserved Protein Sequences of Influenza A Viruses, Avian and Human, as Vaccine Targets

BACKGROUND: Influenza A viruses generate an extreme genetic diversity through point mutation and gene segment exchange, resulting in many new strains that emerge from the animal reservoirs, among which was the recent highly pathogenic H5N1 virus. This genetic diversity also endows these viruses with...

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Detalles Bibliográficos
Autores principales: Heiny, A. T., Miotto, Olivo, Srinivasan, Kellathur N., Khan, Asif M., Zhang, G. L., Brusic, Vladimir, Tan, Tin Wee, August, J. Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2065905/
https://www.ncbi.nlm.nih.gov/pubmed/18030326
http://dx.doi.org/10.1371/journal.pone.0001190