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MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine

Guanosine exerts neuroprotective effects in the central nervous system. Apoptosis, a morphological form of programmed cell death, is implicated in the pathophysiology of Parkinson’s disease (PD). MPP(+), a dopaminergic neurotoxin, produces in vivo and in vitro cellular changes characteristic of PD,...

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Detalles Bibliográficos
Autores principales: Pettifer, Kathleen M., Jiang, Shucui, Bau, Christian, Ballerini, Patrizia, D’Alimonte, Iolanda, Werstiuk, Eva S., Rathbone, Michel P.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072917/
https://www.ncbi.nlm.nih.gov/pubmed/18404453
http://dx.doi.org/10.1007/s11302-007-9073-z

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