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MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine
Guanosine exerts neuroprotective effects in the central nervous system. Apoptosis, a morphological form of programmed cell death, is implicated in the pathophysiology of Parkinson’s disease (PD). MPP(+), a dopaminergic neurotoxin, produces in vivo and in vitro cellular changes characteristic of PD,...
Autores principales: | Pettifer, Kathleen M., Jiang, Shucui, Bau, Christian, Ballerini, Patrizia, D’Alimonte, Iolanda, Werstiuk, Eva S., Rathbone, Michel P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072917/ https://www.ncbi.nlm.nih.gov/pubmed/18404453 http://dx.doi.org/10.1007/s11302-007-9073-z |
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