An inbred colony of oncogene transgenic mice: diversity of tumours and potential as a therapeutic model.

Transgenic mice carrying the activated rat c-neu oncogene under transcriptional control of the MMTV promoter were backcrossed to BALB/c mice, with the aim of developing a model for cancer therapy. A total of 86 of 268 transgene-positive mice in the first five generations developed 93 histologically...

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Detalles Bibliográficos
Autores principales: Thomas, H., Hanby, A. M., Smith, R. A., Hagger, P., Patel, K., Raikundalia, B., Camplejohn, R. S., Balkwill, F. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074278/
https://www.ncbi.nlm.nih.gov/pubmed/8554986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074278/
https://www.ncbi.nlm.nih.gov/pubmed/8554986

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