Inheritance of chromosome 7 is associated with a drug-resistant phenotype in somatic cell hybrids.

A major form of drug resistance in tumour cells known as classical multidrug resistance (MDR) is associated with the overexpression of the mdr1 gene product, the membrane protein P-glycoprotein (P-gp), which acts as an energy-dependent drug efflux pump. In this study the inheritance of P-gp expressi...

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Detalles Bibliográficos
Autores principales: de Silva, M., Kantharidis, P., Wall, D. M., Campbell, L., Vrazas, V., Nadalin, G., Kaczmarczyk, S. J., Hu, X. F., Parkin, J. D., Zalcberg, J. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074323/
https://www.ncbi.nlm.nih.gov/pubmed/8546902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074323/
https://www.ncbi.nlm.nih.gov/pubmed/8546902

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