Tallimustine in advanced previously untreated colorectal cancer, a phase II study.

Tallimustine is a novel benzoyl mustard derivative from distamycin A with a unique mode of action. It is a DNA minor groove binder and produces highly sequence-specific alkylations. Previous studies have shown significant anti-tumour effects in animal models. We performed a phase II study in previou...

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Detalles Bibliográficos
Autores principales: Punt, C. J., Humblet, Y., Roca, E., Dirix, L. Y., Wainstein, R., Polli, A., Corradino, I.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074363/
https://www.ncbi.nlm.nih.gov/pubmed/8611384

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