WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.

Mutations in the WAF1/CIP1 gene were not found in 36 ovarian carcinomas, including tumours with loss of heterozygosity at the WAF1/CIP1 locus and/or lacking p53 mutations. In addition, no association was demonstrable between a polymorphism in a conserved region of the WAF1/CIP1 gene and ovarian carc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, M., Cofer, K. F., Dubeau, L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074480/
https://www.ncbi.nlm.nih.gov/pubmed/8645586
_version_ 1782137975759437824
author Wan, M.
Cofer, K. F.
Dubeau, L.
author_facet Wan, M.
Cofer, K. F.
Dubeau, L.
author_sort Wan, M.
collection PubMed
description Mutations in the WAF1/CIP1 gene were not found in 36 ovarian carcinomas, including tumours with loss of heterozygosity at the WAF1/CIP1 locus and/or lacking p53 mutations. In addition, no association was demonstrable between a polymorphism in a conserved region of the WAF1/CIP1 gene and ovarian carcinoma.
format Text
id pubmed-2074480
institution National Center for Biotechnology Information
language English
publishDate 1996
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20744802009-09-10 WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer. Wan, M. Cofer, K. F. Dubeau, L. Br J Cancer Research Article Mutations in the WAF1/CIP1 gene were not found in 36 ovarian carcinomas, including tumours with loss of heterozygosity at the WAF1/CIP1 locus and/or lacking p53 mutations. In addition, no association was demonstrable between a polymorphism in a conserved region of the WAF1/CIP1 gene and ovarian carcinoma. Nature Publishing Group 1996-06 /pmc/articles/PMC2074480/ /pubmed/8645586 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Wan, M.
Cofer, K. F.
Dubeau, L.
WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title_full WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title_fullStr WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title_full_unstemmed WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title_short WAF1/CIP1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
title_sort waf1/cip1 structural abnormalities do not contribute to cell cycle deregulation in ovarian cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074480/
https://www.ncbi.nlm.nih.gov/pubmed/8645586
work_keys_str_mv AT wanm waf1cip1structuralabnormalitiesdonotcontributetocellcyclederegulationinovariancancer
AT coferkf waf1cip1structuralabnormalitiesdonotcontributetocellcyclederegulationinovariancancer
AT dubeaul waf1cip1structuralabnormalitiesdonotcontributetocellcyclederegulationinovariancancer

Ejemplares similares