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Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skin.
The Myc oncoprotein is associated with cell proliferation and is often down-regulated during cell differentiation. The related Mad transcription factor, which antagonises Myc activity, is highly expressed in epidermal keratinocytes. Mad also inhibits cell proliferation in vitro. To study Mad express...
Autores principales: | Lymboussaki, A., Kaipainen, A., Hatva, E., Västrik, I., Jeskanen, L., Jalkanen, M., Werner, S., Stenbäck, F., Alitalo, R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074494/ https://www.ncbi.nlm.nih.gov/pubmed/8645578 |
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