The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.

Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), int...

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Autores principales: Scott, H. R., McMillan, D. C., Crilly, A., McArdle, C. S., Milroy, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074552/
https://www.ncbi.nlm.nih.gov/pubmed/8664130
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author Scott, H. R.
McMillan, D. C.
Crilly, A.
McArdle, C. S.
Milroy, R.
author_facet Scott, H. R.
McMillan, D. C.
Crilly, A.
McArdle, C. S.
Milroy, R.
author_sort Scott, H. R.
collection PubMed
description Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC.
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spelling pubmed-20745522009-09-10 The relationship between weight loss and interleukin 6 in non-small-cell lung cancer. Scott, H. R. McMillan, D. C. Crilly, A. McArdle, C. S. Milroy, R. Br J Cancer Research Article Markers of the inflammatory response, interleukin 6, C-reactive protein, albumin and full blood count, were measured in non-small-cell lung cancer (NSCLC) patients (n = 21) with and without weight loss ( > 5%). There were significant increases in circulating C-reactive protein (P < 0.001), interleukin 6 (P < 0.01) and platelets (P < 0.01) in the weight-losing group. Moreover, there was a statistically significant correlation (r = 0.785, P < 0.001) between interleukin 6 and C-reactive protein concentrations. These results are consistent with interleukin 6 and the acute phase response promoting weight loss in NSCLC. Nature Publishing Group 1996-06 /pmc/articles/PMC2074552/ /pubmed/8664130 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Scott, H. R.
McMillan, D. C.
Crilly, A.
McArdle, C. S.
Milroy, R.
The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title_full The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title_fullStr The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title_full_unstemmed The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title_short The relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
title_sort relationship between weight loss and interleukin 6 in non-small-cell lung cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074552/
https://www.ncbi.nlm.nih.gov/pubmed/8664130
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