Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.

In the present study organotypic multicellular spheroids (OMS) were used to study the effects of chemotherapeutic agents on malignant gliomas. Compared with the frequently used cell line models, OMS have several advantages with respect to the preservation of the cellular heterogeneity and the struct...

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Detalles Bibliográficos
Autores principales: Kaaijk, P., Troost, D., de Boer, O. J., Van Amstel, P., Bakker, P. J., Leenstra, S., Bosch, D. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074578/
https://www.ncbi.nlm.nih.gov/pubmed/8688320

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