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Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer.

We have assessed the pharmacokinetics, pharmacological and anti-tumour effects of the specific steroidal anti-oestrogen ICI 182780 in 19 patients with advanced breast cancer resistant to tamoxifen. The agent was administered as a monthly depot intramuscular injection. Peak levels of ICI 182780 occur...

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Detalles Bibliográficos
Autores principales:	Howell, A., DeFriend, D. J., Robertson, J. F., Blamey, R. W., Anderson, L., Anderson, E., Sutcliffe, F. A., Walton, P.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1996
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074590/ https://www.ncbi.nlm.nih.gov/pubmed/8688341

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