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K-ras mutations and HLA-DR expression in large bowel adenomas.
A total of 72 sporadic colorectal adenomas in 56 patients were studied for the presence of point mutations in codons 12 and 13 of the K-ras gene and for HLA-DR antigen expression related to clinicopathological variables. Forty K-ras mutations in 39 adenomas were found (54%): 31 (77%) in codon 12 and...
Autores principales: | Norheim Andersen, S., Breivik, J., Løvig, T., Meling, G. I., Gaudernack, G., Clausen, O. P., Schjölberg, A., Fausa, O., Langmark, F., Lund, E., Rognum, T. O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074621/ https://www.ncbi.nlm.nih.gov/pubmed/8679466 |
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