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Receptor-mediated uptake of low-density lipoprotein by B16 melanoma cells in vitro and in vivo in mice.
Selective delivery of cytotoxic anti-neoplastic drugs can diminish the severe side-effects associated with these drugs. Many malignant tumours express high levels of low-density lipoprotein (LDL) receptors on their membranes. Therefore, LDL may be used as a carrier to obtain selective delivery of an...
Autores principales: | Versluis, A. J., van Geel, P. J., Oppelaar, H., van Berkel, T. J., Bijsterbosch, M. K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074664/ https://www.ncbi.nlm.nih.gov/pubmed/8761365 |
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