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RET activation in adult and childhood papillary thyroid carcinoma using a reverse transcriptase-n-polymerase chain reaction approach on archival-nested material.
Activation of the RET tyrosine kinase domain occurs in a proportion of thyroid papillary carcinomas. Three chromosomal rearrangements have been described, of which PTC1 is the commonest. Wide differences (2.5-25%) in frequency of PTC1 in different populations have been reported; it is not clear whet...
Autores principales: | Williams, G. H., Rooney, S., Thomas, G. A., Cummins, G., Williams, E. D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074679/ https://www.ncbi.nlm.nih.gov/pubmed/8761374 |
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