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Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases.
A common characteristic of cancer cells is unrestrained cell division. This may be caused by mutational changes in genes coding for components of cell cycle-controlling networks. Alterations in genes involved in G1 checkpoint control have been registered in many human tumours, and investigations fro...
Autores principales: | Platz, A., Sevigny, P., Norberg, T., Ring, P., Lagerlöf, B., Ringborg, U. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074743/ https://www.ncbi.nlm.nih.gov/pubmed/8826861 |
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