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Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic.
Based on data from the Nordic cancer registries, time-related trends in incidence of Kaposi's sarcoma (KS) were analysed in four ethnically similar populations before the AIDS epidemic. Data were available for different time periods in Denmark (1970-79), Sweden (1958-79), Finland (1953-79) and...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074794/ https://www.ncbi.nlm.nih.gov/pubmed/8912552 |
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author | Hjalgrim, H. Melbye, M. Pukkala, E. Langmark, F. Frisch, M. Dictor, M. Ekbom, A. |
author_facet | Hjalgrim, H. Melbye, M. Pukkala, E. Langmark, F. Frisch, M. Dictor, M. Ekbom, A. |
author_sort | Hjalgrim, H. |
collection | PubMed |
description | Based on data from the Nordic cancer registries, time-related trends in incidence of Kaposi's sarcoma (KS) were analysed in four ethnically similar populations before the AIDS epidemic. Data were available for different time periods in Denmark (1970-79), Sweden (1958-79), Finland (1953-79) and Norway (1953-79). KS was more common among men than among women aged 60 years or more, whereas no differences were observed for younger persons. The incidence of KS differed significantly between the four countries (P = 0.0001); Sweden having the highest and Denmark the lowest rates. Similarly, regional differences in incidence were observed within Sweden, rates being higher in the northern than in the southern areas (Ptrend = 0.002). Overall, in Nordic men the world standardised incidence rose from 0.5/1,000,000 person-years in the period 1953-57 to 1.8/1,000,000 person-years in 1978-79; in Nordic women, the corresponding rates were 0.2/1,000,000 person-years and 0.8/1,000,000 person-years respectively. The rate of increase was similar in Sweden, Finland and Norway (P = 0.14), whereas the short period of observation in Denmark precluded precise assessment of time-related incidence trends. These observations cannot be explained by registrational procedures or known risk factors for KS, and argue that environmental factors play an important role in the development of the disease. |
format | Text |
id | pubmed-2074794 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1996 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20747942009-09-10 Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. Hjalgrim, H. Melbye, M. Pukkala, E. Langmark, F. Frisch, M. Dictor, M. Ekbom, A. Br J Cancer Research Article Based on data from the Nordic cancer registries, time-related trends in incidence of Kaposi's sarcoma (KS) were analysed in four ethnically similar populations before the AIDS epidemic. Data were available for different time periods in Denmark (1970-79), Sweden (1958-79), Finland (1953-79) and Norway (1953-79). KS was more common among men than among women aged 60 years or more, whereas no differences were observed for younger persons. The incidence of KS differed significantly between the four countries (P = 0.0001); Sweden having the highest and Denmark the lowest rates. Similarly, regional differences in incidence were observed within Sweden, rates being higher in the northern than in the southern areas (Ptrend = 0.002). Overall, in Nordic men the world standardised incidence rose from 0.5/1,000,000 person-years in the period 1953-57 to 1.8/1,000,000 person-years in 1978-79; in Nordic women, the corresponding rates were 0.2/1,000,000 person-years and 0.8/1,000,000 person-years respectively. The rate of increase was similar in Sweden, Finland and Norway (P = 0.14), whereas the short period of observation in Denmark precluded precise assessment of time-related incidence trends. These observations cannot be explained by registrational procedures or known risk factors for KS, and argue that environmental factors play an important role in the development of the disease. Nature Publishing Group 1996-11 /pmc/articles/PMC2074794/ /pubmed/8912552 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Hjalgrim, H. Melbye, M. Pukkala, E. Langmark, F. Frisch, M. Dictor, M. Ekbom, A. Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title | Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title_full | Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title_fullStr | Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title_full_unstemmed | Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title_short | Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. |
title_sort | epidemiology of kaposi's sarcoma in the nordic countries before the aids epidemic. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074794/ https://www.ncbi.nlm.nih.gov/pubmed/8912552 |
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