Prolonged intraperitoneal infusion of 5-fluorouracil using a novel carrier solution.

A novel peritoneal carrier solution, Icodextrin 20 (7.5%), has allowed exploration of prolonged, intraperitoneal (i.p.) infusion of the cytotoxic drug 5-fluorouracil (5-FU). A phase I and pharmacokinetic study was performed to determine the toxicities and maximum tolerated dose of prolonged and cont...

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Detalles Bibliográficos
Autores principales: Kerr, D. J., Young, A. M., Neoptolemos, J. P., Sherman, M., Van-Geene, P., Stanley, A., Ferry, D., Dobbie, J. W., Vincke, B., Gilbert, J., el Eini, D., Dombros, N., Fountzilas, G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074829/
https://www.ncbi.nlm.nih.gov/pubmed/8980409

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