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Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

In efforts to develop an effective vaccine, sterilizing immunity to primate lentiviruses has only been achieved by the use of live attenuated viruses carrying major deletions in nef and other accessory genes. Although live attenuated HIV vaccines are unlikely to be developed due to a myriad of safet...

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Detalles Bibliográficos
Autores principales:	Gorry, Paul R, McPhee, Dale A, Verity, Erin, Dyer, Wayne B, Wesselingh, Steven L, Learmont, Jennifer, Sullivan, John S, Roche, Michael, Zaunders, John J, Gabuzda, Dana, Crowe, Suzanne M, Mills, John, Lewin, Sharon R, Brew, Bruce J, Cunningham, Anthony L, Churchill, Melissa J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075523/ https://www.ncbi.nlm.nih.gov/pubmed/17888184 http://dx.doi.org/10.1186/1742-4690-4-66

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