p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.

Fallopian tube carcinoma (FTC) is a rare but lethal gynaecological malignancy. Four out of seven FTCs were identified with three point missense mutations, one single base deletion and one silent point mutation in the p53 gene. Genital-type HPV sequences were not detected. The S-phase fraction of tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Runnebaum, I. B., Köhler, T., Stickeler, E., Kieback, H. R., Kreienberg, R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075926/
https://www.ncbi.nlm.nih.gov/pubmed/8883398
_version_ 1782138092476432384
author Runnebaum, I. B.
Köhler, T.
Stickeler, E.
Kieback, H. R.
Kreienberg, R.
author_facet Runnebaum, I. B.
Köhler, T.
Stickeler, E.
Kieback, H. R.
Kreienberg, R.
author_sort Runnebaum, I. B.
collection PubMed
description Fallopian tube carcinoma (FTC) is a rare but lethal gynaecological malignancy. Four out of seven FTCs were identified with three point missense mutations, one single base deletion and one silent point mutation in the p53 gene. Genital-type HPV sequences were not detected. The S-phase fraction of tumours with mutant and wild-type p53 was 25.74% (median) and 12.55% (median) respectively. IMAGES:
format Text
id pubmed-2075926
institution National Center for Biotechnology Information
language English
publishDate 1996
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20759262009-09-10 p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma. Runnebaum, I. B. Köhler, T. Stickeler, E. Kieback, H. R. Kreienberg, R. Br J Cancer Research Article Fallopian tube carcinoma (FTC) is a rare but lethal gynaecological malignancy. Four out of seven FTCs were identified with three point missense mutations, one single base deletion and one silent point mutation in the p53 gene. Genital-type HPV sequences were not detected. The S-phase fraction of tumours with mutant and wild-type p53 was 25.74% (median) and 12.55% (median) respectively. IMAGES: Nature Publishing Group 1996-10 /pmc/articles/PMC2075926/ /pubmed/8883398 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Runnebaum, I. B.
Köhler, T.
Stickeler, E.
Kieback, H. R.
Kreienberg, R.
p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title_full p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title_fullStr p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title_full_unstemmed p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title_short p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.
title_sort p53 mutation is associated with high s-phase fraction in primary fallopian tube adenocarcinoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075926/
https://www.ncbi.nlm.nih.gov/pubmed/8883398
work_keys_str_mv AT runnebaumib p53mutationisassociatedwithhighsphasefractioninprimaryfallopiantubeadenocarcinoma
AT kohlert p53mutationisassociatedwithhighsphasefractioninprimaryfallopiantubeadenocarcinoma
AT stickelere p53mutationisassociatedwithhighsphasefractioninprimaryfallopiantubeadenocarcinoma
AT kiebackhr p53mutationisassociatedwithhighsphasefractioninprimaryfallopiantubeadenocarcinoma
AT kreienbergr p53mutationisassociatedwithhighsphasefractioninprimaryfallopiantubeadenocarcinoma

Ejemplares similares