Cargando…
A randomised phase II study of sialyl-Tn and DETOX-B adjuvant with or without cyclophosphamide pretreatment for the active specific immunotherapy of breast cancer.
Studies in animal models of mouse mammary carcinoma have shown that ovine submaxillary mucin, which carries multiple sialyl-Tn (STn) epitopes, is effective in stimulating an immune response and inhibiting tumour growth. In similar studies using carbohydrate antigens, pretreatment with low-dose cyclo...
Autores principales: | Miles, D. W., Towlson, K. E., Graham, R., Reddish, M., Longenecker, B. M., Taylor-Papadimitriou, J., Rubens, R. D. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075933/ https://www.ncbi.nlm.nih.gov/pubmed/8883420 |
Ejemplares similares
-
Expression of sialyl-Tn predicts the effect of adjuvant chemotherapy in node-positive breast cancer.
por: Miles, D. W., et al.
Publicado: (1994) -
The Role of Sialyl-Tn in Cancer
por: Munkley, Jennifer
Publicado: (2016) -
Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
por: Loureiro, Liliana R., et al.
Publicado: (2015) -
Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
por: Julien, S, et al.
Publicado: (2009) -
Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy
por: Lima, L, et al.
Publicado: (2013)