Cargando…
Multistage designs for phase II clinical trials: statistical issues in cancer research.
The main objective of phase II clinical trials is to estimate treatment efficacy on a relatively small number of patients in order to decide whether the treatment ought to be studied in large-scale comparative trials. They play a key role in the drug development process, since the results determine...
Autores principales: | Kramar, A., Potvin, D., Hill, C. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075945/ https://www.ncbi.nlm.nih.gov/pubmed/8883425 |
Ejemplares similares
-
Mixed response and time-to-event endpoints for multistage single-arm phase II design
por: Lai, Xin, et al.
Publicado: (2015) -
Optimal multistage designs for randomised clinical trials with continuous outcomes
por: Wason, James MS, et al.
Publicado: (2012) -
Adaptive multiarm multistage clinical trials
por: Ghosh, Pranab, et al.
Publicado: (2020) -
Current statistical issues in clinical cancer research.
por: Altman, D. G., et al.
Publicado: (1993) -
Calculating Stage Duration Statistics in Multistage Diseases
por: Komarova, Natalia L., et al.
Publicado: (2011)