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Aphidicolin markedly increases the platinum sensitivity of cells from primary ovarian tumours.

Enhanced DNA repair has been observed in cisplatin-resistant ovarian cancer cell lines. This resistance can be modulated, on co-incubation with aphidicolin in established cell lines and animal tumour models, by inhibiting DNA polymerases. We describe a study of the in vitro modulation effect of aphi...

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Detalles Bibliográficos
Autores principales:	Sargent, J. M., Elgie, A. W., Williamson, C. J., Taylor, C. G.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1996
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077213/ https://www.ncbi.nlm.nih.gov/pubmed/8956785

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