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Gene conversion limits divergence of mammalian TLR1 and TLR6

BACKGROUND: Toll-like receptors (TLR) recognize pathogen-associated molecular patterns and are important mediators of the innate immune system. TLR1 and TLR6 are paralogs and located in tandem on the same chromosome in mammals. They form heterodimers with TLR2 and bind lipopeptide components of gram...

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Detalles Bibliográficos
Autores principales:	Kruithof, Egbert KO, Satta, Nathalie, Liu, Jia Wei, Dunoyer-Geindre, Sylvie, Fish, Richard J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077338/ https://www.ncbi.nlm.nih.gov/pubmed/17727694 http://dx.doi.org/10.1186/1471-2148-7-148

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