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Pre-mRNA Secondary Structures Influence Exon Recognition

The secondary structure of a pre-mRNA influences a number of processing steps including alternative splicing. Since most splicing regulatory proteins bind to single-stranded RNA, the sequestration of RNA into double strands could prevent their binding. Here, we analyzed the secondary structure conte...

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Detalles Bibliográficos
Autores principales: Hiller, Michael, Zhang, Zhaiyi, Backofen, Rolf, Stamm, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077896/
https://www.ncbi.nlm.nih.gov/pubmed/18020710
http://dx.doi.org/10.1371/journal.pgen.0030204