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Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice

BACKGROUND: Surfactant protein D (SP-D) deficient mice develop emphysema-like pathology associated with focal accumulations of foamy alveolar macrophages, an excess of surfactant phospholipids in the alveolar space and both hypertrophy and hyperplasia of alveolar type II cells. These findings are as...

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Detalles Bibliográficos
Autores principales:	Knudsen, Lars, Ochs, Matthias, MacKay, Rosemarie, Townsend, Paul, Deb, Roona, Mühlfeld, Christian, Richter, Joachim, Gilbert, Fabian, Hawgood, Samuel, Reid, Kenneth, Clark, Howard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078589/ https://www.ncbi.nlm.nih.gov/pubmed/17915009 http://dx.doi.org/10.1186/1465-9921-8-70

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