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Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis

B cell lymphoma 2 (Bcl-2) homology domain 3 (BH3)–only proteins of the Bcl-2 family are important functional adaptors that link cell death signals to the activation of Bax and/or Bak. The BH3-only protein Nbk/Bik induces cell death via an entirely Bax-dependent/Bak-independent mechanism. In contrast...

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Detalles Bibliográficos
Autores principales:	Gillissen, Bernhard, Essmann, Frank, Hemmati, Philipp G., Richter, Antje, Richter, Anja, Öztop, Ilker, Chinnadurai, Govindaswamy, Dörken, Bernd, Daniel, Peter T.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080900/ https://www.ncbi.nlm.nih.gov/pubmed/18025305 http://dx.doi.org/10.1083/jcb.200703040

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