Cargando…

Mitosis persists in the absence of Cdk1 activity when proteolysis or protein phosphatase activity is suppressed

Cellular transition to anaphase and mitotic exit has been linked to the loss of cyclin-dependent kinase 1 (Cdk1) kinase activity as a result of anaphase-promoting complex/cyclosome (APC/C)–dependent specific degradation of its cyclin B1 subunit. Cdk1 inhibition by roscovitine is known to induce prem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skoufias, Dimitrios A., Indorato, Rose-Laure, Lacroix, Françoise, Panopoulos, Andreas, Margolis, Robert L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080905/ https://www.ncbi.nlm.nih.gov/pubmed/18025303 http://dx.doi.org/10.1083/jcb.200704117

Ejemplares similares

Drug resistance dependent on allostery: A P-loop rigor Eg5 mutant exhibits resistance to allosteric inhibition by STLC
por: Indorato, Rose-Laure, et al.
Publicado: (2022)

A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast
por: Harvey, Stacy L., et al.
Publicado: (2011)

Human Survivin Is a Kinetochore-Associated Passenger Protein
por: Skoufias, Dimitrios A., et al.
Publicado: (2000)

Differential Subcellular Localization of Protein Phosphatase-1 α, γ1, and δ Isoforms during Both Interphase and Mitosis in Mammalian Cells
por: Andreassen, Paul R., et al.
Publicado: (1998)

Coordination of Protein Kinase and Phosphoprotein Phosphatase Activities in Mitosis
por: Nasa, Isha, et al.
Publicado: (2018)

Activation of Myosin Phosphatase Targeting Subunit by Mitosis-specific Phosphorylation
por: Totsukawa, Go, et al.
Publicado: (1999)

CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity
por: Zhang, Lin, et al.
Publicado: (2015)

Protein phosphatases in the regulation of mitosis
por: Nilsson, Jakob
Publicado: (2019)

Phosphatases in Mitosis: Roles and Regulation
por: Moura, Margarida, et al.
Publicado: (2019)

Glioblastoma motility occurs in the absence of actin polymer
por: Panopoulos, Andreas, et al.
Publicado: (2011)

Exit from Mitosis in Budding Yeast: Protein Phosphatase 1 is Required Downstream from Cdk1 Inactivation
por: Keaton, Jason M., et al.
Publicado: (2023)

Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis
por: Gavet, Olivier, et al.
Publicado: (2010)

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation
por: Lemmens, Bennie, et al.
Publicado: (2018)

Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
por: Lacroix, Benjamin, et al.
Publicado: (2022)

Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis
por: Wang, Lei, et al.
Publicado: (2022)

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175
por: Ammosova, Tatiana, et al.
Publicado: (2011)

Protein Phosphatases Involved in Regulating Mitosis: Facts and Hypotheses
por: Kim, Hyun-Soo, et al.
Publicado: (2016)

Phosphorylation of AIB1 at Mitosis Is Regulated by CDK1/CYCLIN B
por: Ferrero, Macarena, et al.
Publicado: (2011)

Cdk1 drives meiosis and mitosis through two different mechanisms
por: Adhikari, Deepak, et al.
Publicado: (2012)

Coordinating DNA Replication and Mitosis through Ubiquitin/SUMO and CDK1
por: Galarreta, Antonio, et al.
Publicado: (2021)

Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis
por: Kataria, Meghna, et al.
Publicado: (2019)

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2005)

Proteolysis of Xenopus Cip-type CDK inhibitor, p16(Xic2), is regulated by PCNA binding and CDK2 phosphorylation
por: Zhu, Xi-Ning, et al.
Publicado: (2013)

Sinomenine Inhibits the Growth of Ovarian Cancer Cells Through the Suppression of Mitosis by Down-Regulating the Expression and the Activity of CDK1
por: Qu, Xiaoyan, et al.
Publicado: (2021)

Cdk-counteracting phosphatases unlock mitotic exit
por: Queralt, Ethel, et al.
Publicado: (2008)

The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase
por: Wicky, Sidonie, et al.
Publicado: (2011)

CDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following Mitosis
por: Gayek, A. Sophia, et al.
Publicado: (2016)

Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis
por: Zhong, Li, et al.
Publicado: (2020)

Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA
por: Heine, Simon, et al.
Publicado: (2018)

Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor
por: Lim, Su-Lin, et al.
Publicado: (2020)

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis
por: Yamaguchi, Tomoya, et al.
Publicado: (2005)

CDK1 and PLK1 coordinate the disassembly and reassembly of the nuclear envelope in vertebrate mitosis
por: de Castro, Ines J, et al.
Publicado: (2017)

Phosphorylation of NMDA receptors by cyclin B/CDK1 modulates calcium dynamics and mitosis
por: Rosendo-Pineda, Margarita Jacaranda, et al.
Publicado: (2020)

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
por: Odle, Richard I., et al.
Publicado: (2020)

The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis
por: Basu, Souradeep, et al.
Publicado: (2020)

Human Cdc14B Promotes Progression through Mitosis by Dephosphorylating Cdc25 and Regulating Cdk1/Cyclin B Activity
por: Tumurbaatar, Indra, et al.
Publicado: (2011)

PERSISTENCE OF MESSENGER RNA THROUGH MITOSIS IN HELA CELLS
por: Hodge, L. D., et al.
Publicado: (1969)

Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint
por: Geley, Stephan, et al.
Publicado: (2001)

ASPP2 Is Phosphorylated by CDK1 during Mitosis and Required for Pancreatic Cancer Cell Proliferation
por: Xiao, Yi, et al.
Publicado: (2023)

The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase
por: Kumada, Kazuki, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_ssck9n2j3qsn6m4t4v6upiildb