Cargando…

Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

We have investigated the effects of inhibiting the expression of cofilin to understand its role in protrusion dynamics in metastatic tumor cells, in particular. We show that the suppression of cofilin expression in MTLn3 cells (an apolar randomly moving amoeboid metastatic tumor cell) caused them to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sidani, Mazen, Wessels, Deborah, Mouneimne, Ghassan, Ghosh, Mousumi, Goswami, Sumanta, Sarmiento, Corina, Wang, Weigang, Kuhl, Spencer, El-Sibai, Mirvat, Backer, Jonathan M., Eddy, Robert, Soll, David, Condeelis, John
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2080932/ https://www.ncbi.nlm.nih.gov/pubmed/18025308 http://dx.doi.org/10.1083/jcb.200707009

Ejemplares similares

The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
por: Wang, Weigang, et al.
Publicado: (2006)

Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation
por: Mouneimne, Ghassan, et al.
Publicado: (2004)

WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells
por: Sarmiento, Corina, et al.
Publicado: (2008)

Molecular mechanisms of invadopodium formation: the role of the N-WASP–Arp2/3 complex pathway and cofilin
por: Yamaguchi, Hideki, et al.
Publicado: (2005)

EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells
por: van Rheenen, Jacco, et al.
Publicado: (2007)

Optogenetic control of Cofilin and αTAT in living cells using Z-lock
por: Stone, Orrin J., et al.
Publicado: (2019)

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding
por: Frantz, Christian, et al.
Publicado: (2008)

Role of Cofilin in Epidermal Growth Factor–Stimulated Actin Polymerization and Lamellipod Protrusion
por: Chan, Amanda Y., et al.
Publicado: (2000)

Phosphorylation of Adf/Cofilin Abolishes Egf-Induced Actin Nucleation at the Leading Edge and Subsequent Lamellipod Extension
por: Zebda, Noureddine, et al.
Publicado: (2000)

IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells.
por: Homaidan, Fadia R, et al.
Publicado: (2002)

Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation
por: Goyal, Pankaj, et al.
Publicado: (2013)

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation
por: Oser, Matthew, et al.
Publicado: (2009)

How to engage Cofilin
por: Bukrinsky, Michael
Publicado: (2008)

A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia
por: Nagata-Ohashi, Kyoko, et al.
Publicado: (2004)

Cofilin-1 and Other ADF/Cofilin Superfamily Members in Human Malignant Cells
por: Shishkin, Sergey, et al.
Publicado: (2016)

Cofilin overactivation improves hippocampus-dependent short-term memory
por: Raven, Frank, et al.
Publicado: (2023)

Par-3 for the cofilin course
por: LeBrasseur, Nicole
Publicado: (2006)

LIM kinases: cofilin and beyond
por: Prunier, Chloé, et al.
Publicado: (2017)

Role of Cofilin in Alzheimer’s Disease
por: Wang, Qiang, et al.
Publicado: (2020)

RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells
por: El Atat, Oula, et al.
Publicado: (2019)

Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients
por: Patsialou, Antonia, et al.
Publicado: (2012)

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
por: Davis, Richard C, et al.
Publicado: (2011)

Characterization of Sarcoptes scabiei cofilin gene and assessment of recombinant cofilin protein as an antigen in indirect-ELISA for diagnosis
por: Zheng, Yu, et al.
Publicado: (2016)

Cofilin-induced cooperative conformational changes of actin subunits revealed using cofilin-actin fusion protein
por: Umeki, Nobuhisa, et al.
Publicado: (2016)

Turn by Turn Measurements at the KEK-ATF
por: Renier, Y, et al.
Publicado: (2013)

Cofilin activity is a total coincidence
por: Sedwick, Caitlin
Publicado: (2008)

The role of cofilin in age-related neuroinflammation
por: Alsegiani, Amsha S., et al.
Publicado: (2020)

Cofilin Signaling in the CNS Physiology and Neurodegeneration
por: Namme, Jannatun Nayem, et al.
Publicado: (2021)

Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract
por: Tenkerian, Clara, et al.
Publicado: (2015)

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α(4)β(7) integrin antibody
por: He, Sijia, et al.
Publicado: (2019)

Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling
por: Fostok, Sabreen, et al.
Publicado: (2019)

Cofilin is an essential component of the yeast cortical cytoskeleton
Publicado: (1993)

Roles of ADF/cofilin in actin polymerization and beyond
por: Bamburg, James R, et al.
Publicado: (2010)

Cofilin-1: A Modulator of Anxiety in Mice
por: Goodson, Martin, et al.
Publicado: (2012)

The ADF/cofilin family: actin-remodeling proteins
por: Maciver, Sutherland K, et al.
Publicado: (2002)

Detection of sputum cofilin-1 as indicator of malignancy
por: Rangel, M.P., et al.
Publicado: (2018)

Cofilin-1 Is a Mechanosensitive Regulator of Transcription
por: Domingues, Catarina, et al.
Publicado: (2020)

Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways
por: Nicolas, Samer, et al.
Publicado: (2019)

Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion
por: Al-Koussa, Houssam, et al.
Publicado: (2019)

The Late Endosome is Essential for mTORC1 Signaling
por: Flinn, Rory J., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_mk3onimt52mi6q572rve2qggot