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Changing Mad2 Levels Affects Chromosome Segregation and Spindle Assembly Checkpoint Control in Female Mouse Meiosis I

The spindle assembly checkpoint (SAC) ensures correct separation of sister chromatids in somatic cells and provokes a cell cycle arrest in metaphase if one chromatid is not correctly attached to the bipolar spindle. Prolonged metaphase arrest due to overexpression of Mad2 has been shown to be delete...

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Detalles Bibliográficos
Autores principales:	Niault, Théodora, Hached, Khaled, Sotillo, Rocío, Sorger, Peter K., Maro, Bernard, Benezra, Robert, Wassmann, Katja
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082075/ https://www.ncbi.nlm.nih.gov/pubmed/18043727 http://dx.doi.org/10.1371/journal.pone.0001165

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