A Switch in the Mechanism of Communication between the Two DNA-Binding Sites in the SfiI Restriction Endonuclease

While many Type II restriction enzymes are dimers with a single DNA-binding cleft between the subunits, SfiI is a tetramer of identical subunits. Two of its subunits (a dimeric unit) create one DNA-binding cleft, and the other two create a second cleft on the opposite side of the protein. The two cl...

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Detalles Bibliográficos
Autores principales: Bellamy, Stuart R.W., Milsom, Susan E., Kovacheva, Yana S., Sessions, Richard B., Halford, Stephen E.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2082129/
https://www.ncbi.nlm.nih.gov/pubmed/17870087
http://dx.doi.org/10.1016/j.jmb.2007.08.030

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